SenesTech Announced Results From A Pilot Of Evolve; Reports Over A 12-Month Period, Standardized Tracking-Tunnel Surveys Documented An 88% Reduction In Average Rat Activity Intensity And An 82% Reduction In The Proportion Of Monitoring Locations With Detectable Rat Activity

Rodent-Related 311 Calls in Deployment Area Fell 36% While Citywide Calls Increased

Evolve® Rat Bith ControlTM Expands to Six Chicago-Area SSAs and Wards

SURPRISE, Ariz., Oct. 19, 2026 (GLOBE NEWSWIRE) -- SenesTech, Inc. (NASDAQ:SNES), the leader in rodent birth control and sustainable rodent population management, today announced results from a pilot of Evolve® Rat Birth Control™ in Chicago's Wicker Park Bucktown Special Service Area (SSA) #33. Over a 12-month monitoring period, standardized tracking-tunnel surveys documented an 88% reduction in average rat activity intensity and an 82% reduction in the proportion of monitoring locations with detectable rat activity. These results provide measurable evidence of Evolve's effectiveness in a demanding urban environment, complementing SenesTech's accelerating commercial growth and expanding municipal adoption.

The results represent another significant milestone for SenesTech, following the Company's announcement of preliminary record third-quarter 2026 revenue of approximately $1.1 million, up 40% sequentially and 55% year-over-year, marking its first quarter exceeding $1 million in revenue.

SSA #33 manages one of Chicago's busiest commercial corridors, where well-maintained public landscapes are central to the neighborhood's identity. Persistent Norway rat burrowing in the district's landscape beds and tree pits was damaging perennial plantings and contributing to tens of thousands of dollars in annual landscape-maintenance costs. Seeking to address that activity while responding to community interest in reducing reliance on rodent poisons, the SSA added Evolve to its integrated pest management (IPM) program in April 2025.

Unlike traditional rodenticides, which are designed to kill rodents, Evolve works by targeting reproduction. This provides communities with another approach to long-term rodent population reduction while helping reduce reliance on conventional poisons and their potential risks to pets, wildlife, and the environment.

The SSA deployed 190 Evolve bait stations across approximately two miles of the district, concentrating on the alleyways and landscape beds where rodent activity was most prevalent, and serviced the stations approximately weekly. Beginning in August 2025, tracking-tunnel surveys were conducted every two to three months to measure both the intensity of rat activity, scored from 0 to 3 based on the footprints rats left in each tunnel, and how widely activity was distributed across monitoring locations.

Key findings from the pilot include:

• Rat activity was detected at 74% of monitoring locations in the first survey in August 2025, compared with only 13% in the final survey in July 2026.
• The average rat activity score declined from 1.76 to 0.21, an 88% reduction in activity intensity.
• The largest reduction occurred in flower beds and tree pits, where the average score fell from 1.97 to 0.13. Activity in alleys declined from 1.33 to 0.27.
• Activity remained low through the warmer spring and summer months. August 2025 and July 2026 had comparable weekly average temperatures (79.5°F and 76.0°F) and nearly identical weekly highs, yet activity was substantially lower in July 2026.
• Rodent-related 311 calls within the deployment area declined 36%, from 158 in the 12 months preceding deployment to 101 in the 12 months that followed, while citywide rodent-related 311 calls increased by less than 1% over the same period.