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Assessing Amicus Therapeutics (FOLD) Valuation After Its Recent Share Price Rebound

Simply Wall St·12/13/2025 16:32:40
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Why Amicus Therapeutics Stock Is Back on Investors Radar

Amicus Therapeutics (FOLD) has quietly put together a strong rebound, with the stock up roughly 12% this month and more than 32% over the past 3 months, drawing fresh attention.

See our latest analysis for Amicus Therapeutics.

That recent 6.57% one day share price move, on top of a 30 day share price return of 12%, has pushed Amicus back toward the upper end of its yearly range. This suggests momentum is rebuilding even though the five year total shareholder return remains deeply negative.

If Amicus has put biotech back on your radar, it could be worth seeing what else is setting up for a potential rerating across healthcare stocks.

With shares still trading at a steep discount to analyst targets despite accelerating revenue and a shrinking loss, investors face a key question: Is Amicus an underappreciated rare disease play, or is the market already discounting its next leg of growth?

Most Popular Narrative Narrative: 32.4% Undervalued

With Amicus Therapeutics closing at $10.55 against a narrative fair value of $15.60, the story frames current pricing as materially discounted and sets up a growth driven rerating case.

Expanding patient identification and improving diagnostic pathways have revealed a much larger underdiagnosed and untreated population for Fabry and Pompe diseases than previously estimated, positioning Amicus to drive sustained long-term revenue growth through increased patient penetration and global market expansion.

Read the complete narrative.

Curious how ambitious growth, rising margins and a richer future valuation multiple are all woven together into that single fair value number? The full narrative breaks down the bold revenue ramp, profitability shift and valuation leap that underpin this upside view, but keeps the most surprising assumptions just out of sight until you dive in.

Result: Fair Value of $15.60 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, lingering legal uncertainty and heavy reliance on just a few high value therapies could quickly derail the upbeat growth and valuation thesis.

Find out about the key risks to this Amicus Therapeutics narrative.

Build Your Own Amicus Therapeutics Narrative

If you see the story differently or want to dig into the numbers yourself, you can build a custom view of Amicus in just minutes, Do it your way.

A good starting point is our analysis highlighting 4 key rewards investors are optimistic about regarding Amicus Therapeutics.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.