I think these ASX blue chips shares are primed for a major rebound in 2026

Every market cycle produces its winners and losers. And sometimes, the losers aren't poor-quality companies at all, they are simply dealing with temporary headwinds.

That's what makes times like these so interesting. Several high-quality ASX blue chips have been marked down over the past year, not because their businesses are broken, but because the market has lost patience.

For investors who are willing to look beyond the next quarter, that disconnect can create attractive entry points.

Here are two ASX blue chip shares I believe are primed for a major rebound in 2026.

CSL Ltd (ASX: CSL)

CSL has spent decades earning its reputation as one of the highest-quality companies on the ASX. Its plasma therapies, vaccines, and specialty medicines give it a deeply entrenched position in global healthcare, which is a sector where scale, expertise, and regulatory trust matter enormously.

Yet despite this, CSL shares have been hit hard in 2025. Concerns over a margin recovery at CSL Behring, uncertainty surrounding the Seqirus demerger, weak influenza vaccine rates in the United States, and noise around US tariff policy have clouded what remains a fundamentally strong long-term outlook.

Strip out the market anxiety, and the underlying story hasn't changed for this biotech. Plasma collections continue to rise, new therapies are advancing through its R&D pipeline, and CSL is investing heavily in North American manufacturing to support future growth. The company's earnings power and competitive moat remain intact.

It is rare to see CSL trading at such a meaningful discount to its long-term averages. If sentiment improves in 2026, this blue chip ASX share could be one of the ASX's rebound stories.

Wisetech Global Ltd (ASX: WTC)

WiseTech has transformed global logistics software with its flagship CargoWise platform, which is now used by some of the biggest freight forwarders and supply-chain operators on the planet. Its model is sticky, scalable, and increasingly global, which is the kind of combination tech investors dream about.

However, the past year brought a rare step backwards in market sentiment. Founder controversies, delays to product launches, and a shift to its business model have led to a significant share price pullback. But none of these issues reflect a deterioration in the long-term fundamentals.

CargoWise continues to expand its reach through acquisitions, large enterprise customers are deepening their usage, and WiseTech is still growing at a strong rate.

If its performance improves, it stays clear of further controversies, and transitions successfully to its new business model in 2026, I think the rebound could be sharp for this blue chip ASX share.

The post I think these ASX blue chips shares are primed for a major rebound in 2026 appeared first on The Motley Fool Australia.

Motley Fool contributor James Mickleboro has positions in CSL and WiseTech Global. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended CSL and WiseTech Global. The Motley Fool Australia has positions in and has recommended WiseTech Global. The Motley Fool Australia has recommended CSL. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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