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Boehringer Ingelheim, Zai Lab Collaborate Over Dual DLL3-Targeting Combination To Assess Safety, Tolerability Of Combining Obrixtamig, Boehringer Ingelheim's DLL3/CD3 T-Cell Engager

Benzinga·04/15/2026 12:05:02
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Boehringer Ingelheim and Zai Lab (NASDAQ:ZLAB, HKEX: 9688))) today announced a clinical collaboration focused on pioneering a dual DLL3-targeting combination. The Phase Ib/II study will assess the safety, tolerability, and initial clinical activity of combining obrixtamig, Boehringer Ingelheim's DLL3/CD3 T-cell engager, with zocilurtatug pelitecan (zoci; formerly ZL‑1310), Zai Lab's DLL3-targeting ADC. The study will enroll patients with poorly differentiated NECs and extensive stage SCLC (ES-SCLC); diseases where patients urgently need more effective treatment options.