Insilico Medicine says ISM6331 Phase I data in mesothelioma, advanced solid tumors accepted for ESMO 2026 rapid oral presentation

• Insilico Medicine flagged first-in-human Phase I data for ISM6331, an AI-designed pan-TEAD inhibitor, accepted for rapid oral presentation at ESMO 2026.
• Results have not been presented yet; the talk is scheduled for Oct. 25, 2026 in Madrid.
• The study is assessing safety, tolerability, drug behavior in the body, and early signs of anti-tumor activity in mesothelioma and other advanced solid tumors.
• ISM6331 previously received FDA orphan drug designation for mesothelioma in August 2024, supporting its development path in a niche oncology market.
• The first patient was dosed in the global multicenter Phase I trial in January 2025, marking progression from preclinical work into clinical testing.

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