Australia's Burghof Medical Research Institute recently issued a communiqué saying that a team led by researchers at the institute has drawn up the most detailed chemical signal map to regulate heart function so far, providing a reference for the diagnosis, treatment and prevention of heart disease. According to the communiqué, the researchers tested 87 types of signaling molecules that interact with receptors distributed on heart cells using miniature human heart tissue cultivated in the laboratory; they also measured the intensity of contraction of heart tissue and the activation or closure of related genes under the conditions of stimulating each signaling molecule, thus establishing a comprehensive database linking biological signal transmission to heart function and gene activity. The relevant paper has been published in the American “Cell-Stem Cell” magazine.

Australia's Burghof Medical Research Institute recently issued a communiqué saying that a team led by researchers at the institute has drawn up the most detailed chemical signal map to regulate heart function so far, providing a reference for the diagnosis, treatment and prevention of heart disease. According to the communiqué, the researchers used miniature human heart tissue cultivated in the laboratory to test 87 types of signaling molecules that interact with receptors distributed on heart cells; they also measured the intensity of contraction of heart tissue and the activation or closure of related genes under the conditions of stimulating each signaling molecule, thus establishing a comprehensive database linking biological signal transmission to heart function and gene activity. The relevant paper has been published in the American “Cell-Stem Cell” magazine.