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Pharvaris Announces Statistically Significant And Clinically Meaningful Topline Results From Its CHAPTER-3 Pivotal Phase 3 Study Evaluating Deucrictibant Extended-Release Tablet For Prevention Of HAE Attacks; Primary Endpoint And All Secondary Efficacy Endpoints Were Met With Statistical Significance

Benzinga·09/08/2026 10:54:31
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  • Primary endpoint met: 83% attack rate reduction versus placebo (p<0.0001) in the first and only prophylaxis Phase 3 study in all three types of HAE
  • 87% attack rate reduction versus placebo observed in people with HAE Type 1 or Type 2
  • All secondary efficacy endpoints met with statistical significance
  • Well-tolerated safety profile of deucrictibant XR demonstrated
  • Conference call and webcast today at 8:00 a.m. EDT