Clearmind Engages Polyrizon To Apply Proprietary Intranasal Hydrogel Technology To Develop Optimized Formulation Of Clearmind's MEAI For Treatment Of Addiction-Related Disorders, Weight Loss And Other CNS Conditions

Collaboration aims to enhance bioavailability and support clinical advancement of Clearmind's lead MEAI candidate for addiction-related and other CNS disorders

Vancouver, Canada, Feb. 06, 2026 (GLOBE NEWSWIRE) -- Clearmind Medicine Inc. (NASDAQ:CMND), (FSE: CWY0) ("Clearmind" or the "Company"), a clinical-stage biotech company focused on the discovery and development of novel neuroplastogen-derived therapeutics to solve major under-treated health problems, today announced that it has entered into a development agreement with Polyrizon Ltd. (NASDAQ:PLRZ) ("Polyrizon"), a pre-clinical-stage biotechnology company developing advanced intranasal delivery solutions.

Under the agreement, Clearmind has engaged Polyrizon to apply its proprietary intranasal hydrogel technology to develop an optimized formulation of Clearmind's lead proprietary compound, MEAI (5-methoxy-2-aminoindane- a next-generation, non-hallucinogenic neuroplastogen designed for the treatment of addiction-related disorders, weight lossand other central nervous system (CNS) conditions.

This strategic collaboration integrates Clearmind's expertise in non-hallucinogenic neuroplastogens with Polyrizon's specialized intranasal delivery platform. The objective is to create a novel intranasal MEAI formulation that will support Clearmind's ongoing and future clinical development programs.